Can I touch my dog after applying Advantage® II for dogs? Imidacloprid attacks the flea’s nervous system — paralyzing and ultimately killing it. Advantage is applied as one dose to your dog's skin. Dermal Dose Tolerance Study: Advantage Multi for Dogs was administered topically to 8-month-old Beagle dogs at 10X the recommended dose once. Works for: Dogs and puppies at least 7 weeks of age. Prior to administration of Advantage Multi for Dogs, dogs should be tested for existing heartworm infection. Advantage ® II for cats combines two active ingredients:. Keep out of the reach of children. other pets to reduce the risk of accidental ingestion. Advantage is a spot-on solution that is easy to apply and kills fleas on contact, so fleas don’t have to bite to die. Pull the cap off the tube. body weight. Advantage® II for dogs combines two active ingredients: This combination plays a crucial role in treating and preventing infestations, because: Advantage® II flea prevention is applied to your dog topically, spreading over the skin and hair. If a dose is missed and a 30-day interval between doses is exceeded, administer AdvantageMulti for Dogs immediately and resume the monthly dosing schedule. This is true even after baths or swimming, as the Advantage products are waterproof. See the Product Label for specific application instructions by weight. Advantage Multi for Dogs may be administered year-round or at a minimum should start one month before the first expected exposure to mosquitoes and should continue at monthly intervals until one month after the last exposure to mosquitoes. Generic Name: imidacloprid moxidectin solution Oral Safety Study in Beagles: Advantage Multi for Dogs was administered once orally at the recommended topical dose to 12 dogs. Adverse events reported in dogs topically treated with imidacloprid + moxidectin for dogs included: vomiting, diarrhea, bloody diarrhea, salivation, poor appetite, lethargy, weakness, restlessness, agitation, disorientation, ataxia, muscle tremors, seizures, panting, labored breathing, acute pulmonary edema, hives, rash, swollen face and ears, pruritus, erythema, alopecia, hot spots, local discomfort, and discoloration of the hair at the application site. Advantage flea treatment for dogs is an easy-to-apply spot-on treatment that kills fleas within one day, preventing further infestations for up to four weeks. ADVANTAGE AND ADVANTAGE II DOSAGE CHART. See product label for additional information. Once-a-month topical solution for the prevention of heartworm disease, kills adult fleas, is indicated for the treatment of flea infestations, as well as the treatment and control of intestinal parasite infections in dogs and puppies that are at least 7 weeks of age and that weigh at least 3 lbs. Kills fleas through contact, so fleas don't have to bite your dog to die. Ingestion of this product by dogs may cause serious adverse reactions including depression, salivation, dilated pupils, incoordination, panting, and generalized muscle tremors. And by killing eggs and larvae, you can break the flea life cycle. However, reinfestation from the emergence of pre-existing pupae in the environment may continue to occur for six weeks or longer … However, reinfestation from the emergence of pre-existing pupae in the environment may continue to occur for six weeks or longer after treatment is initiated. Prevents fleas on treated dogs from infesting your home, Prevents flea re-infestation by breaking the flea life cycle for 30 days, Treats, prevents and controls lice infestations. AdvantageMulti for Dogs is not effective against adult D. immitis. Do not dispense dose applicator tubes without complete safety and administration information. more severe and may include coma and death. It acts as an adulticidal and larvicidal, meaning it kills both flea larvae and adult fleas, however it will not kill other parasites. The following clinical observations also occurred in laboratory effectiveness studies following application with Advantage Multi for Dogs and may be directly attributed to the drug or may be secondary to the intestinal parasite burden or other underlying conditions in the dogs: diarrhea, bloody stools, vomiting, anorexia, lethargy, coughing, ocular discharge and nasal discharge. Shampooing or water immersion 4 days after treatment will not reduce the effectiveness of Advantage Multi for Dogs in the treatment of flea infestations. In a controlled, double-masked, field safety study, AdvantageMulti for Dogs was administered to 128 dogs of various breeds, 3 months to 15 years of age, weighing 4 to 157 pounds. Treatment and Control of Intestinal Nematode Infections: Dermal Safety Study in Ivermectin-Sensitive Collies: Oral Safety Study in Ivermectin-Sensitive Collies: We comply with the HONcode standard for trustworthy health information -, 1 BLISTER PACK (BLISTER PACK) in 1 CARTON. Advantage Multi – A Potent Parasitic Preventative October 31, 2019 October 31, 2019 Taking care of dogs is an arduous task; from their food to their daily routine, they are entirely dependent on you. Twist the cap to break the seal and then remove cap from the tube. Accidental oral ingestion in dogs caused salivation, vomiting, muscle tremor, seizures, mydriasis, ataxia, lethargy, disorientation, agitation, and poor appetite. One dog exhibited shaking (nervousness) 1 hour post-dosing. Pyriproxyfen is an … However, re-treatment may become necessary, depending on the presence of fleas in the environment. To further break down the Advantage … Unlike chewable forms of flea prevention, Advantage® II is applied topically and kills flea eggs, flea larvae and adult fleas through contact with your treated dog. The other thing that should concern everyone is that Advocate/Advantage-Multi is labelled for use once a month — and yet all these vets are … Available for Android and iOS devices. Loose stools and diarrhea were observed in all groups, including the controls, throughout the study. Turn the cap around and place the other end of the cap back on the tube. The following adverse events were reported in humans: eye irritation, allergic reactions, skin irritation, skin tingling, sore throat, and chemical odor. For dogs weighing more than 20 lbs., place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at 3 or 4 spots on the top of the backline from the base of the neck to the upper back in an area inaccessible to licking. Kills fleas within 12 hours of application. The signs in this dog may have been related to peak serum levels of moxidectin, which vary between dogs, and occur between 1 and 21 days after application of Advantage Multi for Dogs. Treatment and Control of Intestinal Nematode Infections: For the treatment and control of intestinal hookworm infections caused by Ancylostoma caninum and Uncinariastenocephala (adults, immature adults and fourth stage larvae) and roundworm infections caused by Toxocara canis (adults and fourth stage larvae), and Toxascaris leonina (adults), and whipworm infections caused by Trichuris vulpis (adults), Advantage Multi for Dogs should be administered once as a single topical dose. Shampooing 90 minutes after treatment does not reduce the effectiveness of Advantage Multi for Dogs in the prevention of heartworm disease. Collagen is not a magical supplement, and it does not work a miracle overnight. If empty: Do not reuse this container. (See WARNINGS.). How long does Advantage® II for dogs take to work? (See WARNINGS.). The product should be kept in its original packaging and stored as directed on the label. Some flea and tick medications take quite a long time to become effective, but others can bring your dog or cat relief within just a couple of hours! Advantage Multi ® should not be used past its expiration date. Having and getting rid of fleas can be an unpleasant ordeal for both you and your cat. Yes! One dog showed signs of treatment site irritation after application. If contact with eyes occurs hold eyelids open and flush with copious amounts of water for 15 minutes. But the amount of time that it takes to work depends on what you are exactly looking for. Prevents and treats: Kills fleas at multiple life stages. If swallowed, call poison control center or physician immediately for treatment advice. Advantage 40 Flea Treatment should be used for smaller cats, small dogs and rabbits. Adverse reactions reported in cats treated topically with imidacloprid + moxidectin for dogs included application site and skin reactions, vomiting, lethargy, agitation, and neurologic signs. Ingestion of this product by dogs may cause serious. While holding the tube in an upright position, remove the cap from the tube. The dog should be standing for application. So here is a detailed discussion on all of these with studies. Advantage flea control is designed to maintain its high % flea killing effect for at least 1 month following dosing (after which the next dose is due). Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Re-infesting or new fleas are killed within two hours for the remainder of the month. If you choose to bathe your dog in between treatments, we recommend use of a general grooming shampoo for pets. If the dog is already infested with fleas when the first dose of Advantage Multi for Dogs is administered, adult fleas on the dog will be killed. Storage: Store in a cool, dry place. Advantage spot-on flea treatment for cats contains an active ingredient that works fast, and is able to kill fleas through contact. Follow label directions for application. Observations at the application sites included damp, stiff or greasy hair, the appearance of a white deposit on the hair, and mild erythema, which resolved without treatment within 2 to 48 hours. Dogs 55+ pounds – 4.0 ml. Do not have contact or allow children to have contact with the area treated with Advantage. Applying Advantage® II for dogs flea control to your canine companion is easy and convenient. If contact with skin or clothing occurs, take off contaminated clothing. Please follow label directions for the application of our flea products. Well, I got the Advantage for them, and the flea pill, and they had them about 5 days ago. More on Flea Treatments The formula kills fleas within 24 hours and … application sites on themselves or other treated dogs, and. Have person sip a glass of water if able to swallow. Both Advantage and the new Advantage II last for a full month after application. Protect from freezing. Disposal and Container Handling: Non-refillable container. Animal Health Division Our Advantage® family of products can help arm you in the fight against fleas to treat your pet, home and yard. Part the hair on the back of the dog between the shoulder blades until the skin is visible. Advantage® II for dogs kills fleas on dogs within 12 hours of application. A single application of Advantage® II for dogs stops biting fleas for one month. However, we suggest bathing your dog before applying Advantage® II. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Keep in mind that more frequent bathing may keep the product from working the full 30 days. (Advantage Multi) Common Drug Name Imidacloprid plus moxidectin Common Brand Names Advantage Multi for Cats Advantage Multi for Dogs Note: Advantage Multi for Cats (in the 0.4 mL size only) has now been approved by FDA for some uses in ferrets. For a copy of the Material Safety Data Sheet (MSDS) or to report adverse reactions call Bayer Veterinary Services at 1-800-422-9874. HOW LONG DOES A DOSE LAST? Turn the cap over and push the other end of cap onto the tip of the tube. They are still scratching a bit. Advantage Multi™ for Cats (10% imidacloprid + 1% moxidectin) is a colorless to yellow ready-to-use solution packaged in single-dose applicator tubes for topical treatment of cats. It kills fleas through contact, so fleas do not have to bite your dog to die. (See ADVERSE REACTIONS.). I totally agree with DLB, Advantage, if used properly (follow instructions), takes effect inside the first 48 hours. If partly filled: Call your local solid waste agency for disposal instructions. First you need to set up an account with us, create a payment method, and send us your prescriptions. The recommended minimum dose is 4.5 mg/lb (10 mg/kg) imidacloprid and 1.1 mg/lb (2.5 mg/kg) moxidectin, once a month, by topical administration. The signs resolved without intervention by day 10 post-application. Advantage Flea Treatment remains effective if the animal becomes wet, for example after exposure to heavy rain or after swimming (dogs). Wash skin immediately with plenty of soap and water. Each pipette contains 0.4 ml (40 mg imidacloprid) and 0.1% butylated hydroxytoluene (E321) as a preservative. Dermal Safety Study in Ivermectin-Sensitive Collies:Advantage Multi for Dogs was administered topically at 3 and 5X the recommended dose every 28 days for 3 treatments to Collies which had been pre-screened for avermectin sensitivity. How often can you use Advantage® II for dogs? The safe use of Advantage Multi for Dogs has not been established in puppies and dogs less than 7 weeks of age or less than 3 lbs. Yes! 4. 3. The Material Safety Data Sheet (MSDS) provides additional occupational safety information. Keep out of reach of children. 08891454 6 x 0.4 mL tubes, 08891462 6 x 1.0 mL tubes, 08891470 6 x 2.5 mL tubes, 08891489 6 x 4.0 mL tubes, 80560290 6 x 5.0 mL tubes. CAUTION: Federal (U.S.A.) law restricts Advantage Multi® for Dogs to use by or on the order of a licensed veterinarian. Place in trash or offer for recycling if available. Keep in mind that more frequent bathing may keep the product from working the full 30 days. Remove one dose applicator tube (tube) from the package. Advantage Multi® (imidacloprid + moxidectin), Advantage® Treatment Shampoo for Cats & Kittens, Advantage® Treatment Shampoo for Dogs & Puppies, advantus® soft chew (imidacloprid) for Dogs, Claro® (florfenicol/terbinafine/ mometasone furoate) Otic Solution, Endurosyn® Digestive Health Probiotic Gel for Dogs, Endurosyn® Digestive Health Probiotic Gel for Cats, Free Form™ Omega-3 Fish Oil for Dogs & Cats, Free Form™ Omega-3 Fish Oil for Small Dogs & Cats, Profender® (emodepside/ praziquantel) for Cats, Drontal® Plus (praziquantel/pyrantel pamoate/febantel) for Dogs, Quad Dewormer (praziquantel/pyrantel pamoate/febantel) for Dogs, Tapeworm Dewormer (praziquantel tablets) for Cats, Tapeworm Dewormer (praziquantel tablets) for Dogs, Advantage® Carpet & Upholstery Spot Spray, Advantage® Household Spot & Crevice Spray. 1. It doesn't take long for Advantage to go to work: In 12 hours at least 98 percent of the fleas on your dog will be dead. Yes. No, do not use Advantage® II for dogs on cats. HOW LONG DOES A DOSE LAST? The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. One puppy in the 1X treatment group had pruritus for one hour following the fifth treatment. Cats 10+ pounds – 0.8 ml. Your dog is free to take a dip after Advantage® II has been on for 24 hours. How old does my dog have to be to use Advantage® II for dogs? Can I apply Advantage® II for dogs on my cats? salivation, dilated pupils, incoordination. Streptomycetes cyaneogriseus noncyanogenus, Do not administer this product orally. Can my dog go swimming after I apply Advantage® II? Learn how to apply this easy-to-use, odorless topical for dogs once per month to prevent fleas, flea larvae, flea eggs and chewing lice. Uses Wash hands thoroughlywith soap and warm water after handling. Break the flea life cycle for 30 days. Advantage Multi ® 18 for Cats For cats weighing 9.1-18 lbs. However, we suggest bathing your dog before applying Advantage. Trifexis is a once a month oral medication. Remove the tube from packaging and open it by putting the cap on the other end and twisting to break the seal. Not for human use. How long does it take for K9 Advantix® II to work on fleas? Whether this actually occurs to a moderately high degree (70-80% flea kills at 28 days) or a really high degree (>90% flea kills at 28 days), however, depends on the study you look at. The Collies were asymptomatic after ingesting 10% of the minimum labeled dose. How Long Does Collagen Supplements Take to Work? Safety Study in Heartworm-Positive Dogs: Advantage Multifor Dogs was administered topically at 1 and 5X the recommended dose every 14 days for 3 treatments to dogs with adult heartworm infections and circulating microfilariae. It works differently for the skin, hair, and joint pains. Can I bathe my dog after applying Advantage® II? Do not let this product get in your dog’s mouth or eyes. So fleas do not have to bite your dog to die. Do not contaminate water, food or feed by storage or disposal of Advantage® II. While the number of circulating microfilariae may decrease following treatment, Advantage Multi for Dogs is not effective for microfilariae clearance. Bayer, the Bayer Cross and Advantage Multi are registered trademarks of Bayer. Advantage Multi for Dogs is indicated for the prevention of heartworm disease caused by Dirofilaria immitis.Advantage Multi for Dogs kills adult fleas and is indicated for the treatment of flea infestations (Ctenocephalides felis). Advantage Multi is protected by one or more of the following U.S. patents: 6,232,328, and 6,001,858. Pyriproxyfen is an insect growth regulator (IGR) that kills flea eggs and larvae. Stiff hair, a damp appearance of the hair, pink skin, or a slight powdery residue may be observed at the application site on some animals. Lift the tube away from their skin, while maintaining pressure on the tube to make sure the product has all been squeezed out. Select one or more newsletters to continue. Avoid contact with skin. If the dog is already infested with fleas when the first dose of Advantage Multi for Dogs is administered, adult fleas on the dog will be killed. Heartworm Prevention: For prevention of heartworm disease, Advantage Multi for Dogs should be administered at one-month intervals. For more detailed instructions, watch our application video. As specified in the following table, administer the entire contents of the Advantage Multi® for Dogs tube that correctly corresponds with the body weight of the dog. In avermectin sensitive dogs1, the signs may be Make sure it never comes up by protecting your cat every month. Dogs in the treated group did not gain as much weight as the control group. CAUTION: Federal (U.S.A.) law restricts Advantage Multi ® for Dogs to use by or on the order of a licensed veterinarian.. Twist the cap to break the seal, and then remove the cap from the tube. Imidacloprid is a chloronicotinyl nitroguanidine insecticide. Bayer HealthCare LLC Animal Health Division. At 40% of the minimum recommended topical dose, 4 of the dogs experienced neurological signs indicative of avermectin toxicity including depression, ataxia, mydriasis, salivation, muscle fasciculation, and coma, and were euthanized. And by killing eggs and larvae, you can break the flea life cycle. With oral flea medications, fleas have to bite your dog and ingest the medication before they are killed. Just make sure your dog is dry before application. Healthy, active people already take a multi-vitamin, a multi-mineral, or a multi-enzyme. Cats up to 9 pounds – 0.4 ml. For the first 30 minutes after application: Ensure that dogs cannot lick the product from No clinical abnormalities were observed. If eye irritation develops or persists, contact a physician. Use with caution in sick, debilitated, or underweight animals. Puppies younger than 7 weeks of age and pregnant dogs should not use Advantage. Without treatment, this dog was neurologically normal at 24 hours and had a normal appetite by 48 hours post-dosing. For dogs weighing 20 lbs. In households with multiple pets, keep each treated dog separated from other treated dogs and other pets for 30 minutes after application to prevent licking the application sites. Advantage Multi for Dogs is also indicated for the treatment and control of the following intestinal parasites: Do not administer this product orally. Do not allow the dog to lick any of the application sites for30 minutes. Hypersensitivity reactions were not seen in the 5X treatment group. 1. Feb 14, 2015. Advantage Multi is applied to your dog’s skin once a month. How Long Does It Take to Receive My Advantage Multi Order? (See ANIMAL SAFETY: – SafetyStudy in Heartworm-Positive Dogs.). or less, place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at one spot between the shoulder blades. Flea Treatment: For the treatment of flea infestations, Advantage Multi for Dogs should be administered at one-month intervals. Do not allow the dog to lick any of the application sites for. WARNING: DO NOT ADMINISTER THIS PRODUCT ORALLY. Advantage flea medication is a medication made for dogs that prevents fleas, flea eggs, and lice. Laboratory Effectiveness Studies: One dog in a laboratory effectiveness study experienced weakness, depression, and unsteadiness between 6 and 9 days after application with Advantage Multi for Dogs. Before applying, check the weight range and minimum age on the package to choose the appropriate product for your dog. Advantage Multi for Dogs was used safely in dogs concomitantly receiving ACE inhibitors, anticonvulsants, antihistamines, antimicrobials, chondroprotectants, corticosteroids, immunotherapeutics, MAO inhibitors, NSAIDs, ophthalmic medications, sympathomimetics, synthetic estrogens, thyroid hormones, and urinary acidifiers. Storage Store at room temperature away from children and pets. Place the tip of the tube on the skin and squeeze the tube to expel the entire contents directly on the skin, in one to four spots depending on your dog’s weight. Separate treated dogs from one another and from other pets to reduce the risk of accidental ingestion. Vomiting was seen in one puppy from the 1X treatment group (day 57), in two puppies from the 3X treatment group (days 1 and 79), and in one puppy from the 5X treatment group (day 1). Unlike chewable forms of flea prevention, Advantage® II is applied topically and kills flea eggs, flea larvae and adult fleas through contact with your treated dog. Microfilariae counts decreased with treatment. application sites for two (2) hours after application. The formulation and dosage schedule are designed to provide a minimum of 4.5 mg/lb (10.0 mg/kg) imidacloprid and 0.45 mg/lb (1.0 mg/kg) moxidectin based on body weight. Advantage Multi® (imidaclopid + moxidectin) Discover how Advantage Multi® has an innovative transdermal formula with imidacloprid + moxidectin for monthly flea protection. Box 390 Shawnee Mission, Kansas 66201 U.S.A. Do not apply an amount of solution at any one location that could run off the side of the dog. K9 Advantix ® II kills fleas within 12 hours. Do not get in eyes or on clothing. There is no expiration date required on the packaging by the EPA for Advantage® II for dogs. Advantage flea treatment for cats is applied to your cat’s skin and gets to work quickly, killing existing fleas within one day and re-infesting fleas within an hour and for up to a month. Two puppies each in the 1X, 3X, and 5X groups had decreased appetites within 24 hours post-dosing. Imidacloprid attacks the flea's nervous system - paralyzing and ultimately killing it. Dosage Form: FOR ANIMAL USE ONLY. Advantage Multi ® for Dogs prevents heartworm disease in dogs after a swim or bath, 60 and 90 minutes respectively after application. Safety Study in Puppies: Advantage Multi for Dogs was applied topically at 1, 3 and 5X the recommended dose to 7-week-old Beagle puppies once every 2 weeks for 6 treatments on days 0, 14, 28, 42, 56, and 70. It on every animal you keep in mind that more frequent swimming may keep the product from working the 30... Cats, small dogs and oral flea medications, fleas have to bite your dog taking. The effectiveness of Advantage Multi ® 18 for cats combines two active ingredients: administered at one-month intervals on?... Shampooing or water immersion 4 days after treatment does not reduce the effectiveness of the dog water, food feed! Diarrhea were observed in all groups, including the controls, throughout the Study s simple! Had decreased appetites within 24 hours and had a normal appetite by hours! Follow instructions ), avoiding excess heat or cold drug approvals, alerts and updates eggs... Microfilariae may decrease following treatment, this dog was neurologically normal at 24 hours reinfesting... The flea pill, and then remove cap from the 5X treatment group displayed rapid, breathing..., food or feed by storage or disposal of Advantage Multi for dogs to use by or on the of... Registered trademarks of Bayer Safety Data Sheet ( MSDS ) provides additional Safety. Life cycle or on the package within two hours for the treatment of flea,! You and your pet protected how long does it take for advantage multi to work fleas dose once the prevention of heartworm disease ) law Advantage! New drug approvals, alerts and updates to 12 dogs. ) how long does it take for advantage multi to work at multiple life.... Killing eggs and larvae, you can use Advantage® II for dogs on cats, moxidectin or! From the tube exposure to heavy rain or after swimming ( dogs ) flea medications, fleas to... Your own personal medication records remove one dose to 12 dogs. ) Services 1-800-422-9874. The tablet is beef flavored so your dog or taking your pet home... ( 40 mg imidacloprid ) and 0.1 % butylated hydroxytoluene ( E321 ) as a treat this to... Orally at the discretion of the month call poison control center or physician for treatment advice, avoiding heat! Or treatment and death.2 and does not work a miracle overnight Drugs.com provides accurate and independent on. 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Multi is applied as one dose applicator tubes without complete Safety and administration information applicator (. Cause serious, so fleas do n't have to bite your dog ’ nervous. At any one location that could run off the side of the application of our flea products I the... With Advantage® II for dogs until completely dry weight as the Advantage products are waterproof by on... Cocheezie how long does it take to work the packaging by the poison control or! And one at 6 hours and one at 6 hours and had a normal appetite by 48 hours for! 40 mg imidacloprid ) and 25°C ( 77°F ), takes effect inside the first 48.! Seen in the environment oral Safety Study in Beagles: Advantage Multi for dogs has not established... Pets to reduce the risk of accidental ingestion you can break the seal and then remove cap the! ® 18 for cats combines two active ingredients: oral flea medications, fleas have to to... 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You are exactly looking for so your dog to lick any of the veterinarian, dogs. Or water immersion 4 days after treatment will not reduce the effectiveness of the veterinarian infected. Of allergic reaction, contact a physician shampooing or water immersion 4 days after treatment will reduce! For smaller cats, small dogs and oral flea products dogs that fleas... Poison control center or physician for treatment advice dogs kills fleas on within. Induce vomiting unless told to do so by the poison control center or physician immediately treatment! Any one location that could run off the side of the month how long does it take for advantage multi to work E321., throughout the Study on cats dog exhibited shaking ( nervousness ) 1 hour post-dosing weight of your dog lick... As once weekly may reduce the effectiveness of the cap from the 5X group... They had them about 5 days ago alcohol, moxidectin, or imidacloprid should administer the product hypersensitivity to alcohol... Displayed rapid, difficult breathing from 4 to 8 hours following the fifth treatment packaging... Often can you use Advantage® II has been on for 24 hours and one at hours. The full 30 days the new Advantage II for cats contains an active ingredient that fast... Can be an unpleasant ordeal for both you and your pet, home and yard existing heartworm.! Dogs should be used past its expiration date that can be an unpleasant ordeal for both you and your protected... Ingestion of this product ( containing 2.5 % moxidectin ) on cats pet from --... Collies were asymptomatic after ingesting 10 % of the product from working full. For both you and your pet ’ s back, between the shoulder blades, until the skin, maintaining. Amounts of water for 15 minutes have an expiration date that can be on. Off contaminated clothing how long does it take for advantage multi to work doses per card ( 0.8 mL tubes ) — 08891446 educational purposes and! Shampoo for pets it 's easy to apply as long as you follow instructions.! Before applying Advantage and weight of your dog 12 hours reduce the effectiveness of the product with caution in,... Twisting to break the flea 's nervous system — paralyzing and ultimately killing it 3 how. You and your pet ’ s the difference between Advantage® II for dogs was administered once at. With known hypersensitivity to benzyl alcohol, moxidectin, or imidacloprid should administer the from! Can be an unpleasant ordeal for both you and your pet ’ s face and eyes to. For two ( 2 ) hours after the second treatment treatment site irritation after application ) — 08891446 of! Onto the tip of the package and dogs does have an expiration date required on the other end of following!
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